Liposomal Vitamin D3 50% 70%

Cholecalciferol (Vitamin D3) — Liposomal Bulk Raw Material for Anti-Aging & Beauty

Liposomal Vitamin D3 delivers cholecalciferol—the secosteroid hormone precursor—at 50% and 70% liposomal concentrations specifically optimized for nutricosmetic oral beauty formulations. Beyond its well-known role in calcium metabolism, vitamin D3 acts as a potent regulator of keratinocyte differentiation, antimicrobial peptide production, and MMP-1 expression in the skin. Liposomal encapsulation ensures efficient fat-soluble vitamin absorption and protects the molecule from degradation during supplement manufacturing and storage.

Available Purity Grades

• Cholecalciferol 50% 70% (HPLC) — Liposomal powder with phosphatidylcholine encapsulation for enhanced bioavailability.

Why Choose Our Liposomal Cholecalciferol?

• Skin Barrier Integrity: Vitamin D3 regulates the expression of filaggrin, claudin-1, and involucrin—critical proteins that maintain the stratum corneum barrier, preventing moisture loss and environmental allergen penetration.
• Keratinocyte Differentiation: Controls the proliferation-to-differentiation switch in epidermal keratinocytes, ensuring proper cell maturation and preventing the hyperproliferative, parakeratotic patterns seen in aging skin.
• MMP-1 Transcriptional Suppression: Downregulates MMP-1 collagenase gene expression through VDR-mediated signaling, reducing collagen degradation in UV-exposed and chronologically aged dermal tissue.
• Antimicrobial Peptide Induction: Stimulates cathelicidin (LL-37) and defensin production in keratinocytes, enhancing the skin's innate immune defense against pathogens that can trigger inflammatory collagen damage.
• Fat-Soluble Bioavailability: Liposomal encapsulation mimics the micellar transport mechanism used for dietary fat absorption, significantly improving the oral bioavailability of this fat-soluble secosteroid.
• Immune Modulation for Skin: Shifts T-cell populations away from pro-inflammatory Th17 phenotypes toward regulatory T-cells in the skin, reducing autoimmune-mediated inflammation that accelerates collagen loss.

Target Applications

• Beauty-From-Within Supplement Brands: Nutricosmetic companies creating daily beauty capsules or gummies that address vitamin D deficiency while simultaneously supporting skin barrier function and collagen preservation.
• Immune-Skin Axis Brands: Brands developing holistic supplements that connect immune health with skin wellness, leveraging vitamin D3's dual role in systemic immunity and dermal integrity.

Quality & Compliance

• GMP-certified production facilities
• Liposomal encapsulation verified by DLS particle size analysis
• COA provided with every shipment
• Heavy metals compliant (Pb ≤ 2 ppm, As ≤ 1 ppm)
• Custom packaging and private labeling available
• Stable shelf life: 24 months (cool, dry storage, protected from light)

Bulk Supply & OEM Service

We supply liposomal Cholecalciferol in bulk quantities (sample to 25 kg drums) for B2B buyers, contract manufacturers, and private-label brands. Contact our technical team for quotes, sample requests, or formulation consultation.