Liposomal Ergothioneine 50% 70%

L-Ergothioneine (EGT) — Liposomal Bulk Raw Material for Anti-Aging & Beauty

Liposomal Ergothioneine delivers L-ergothioneine, a rare thiol antioxidant with a dedicated cellular transporter (OCTN1) that actively accumulates it in skin tissues. Unlike generic antioxidants that are rapidly consumed, EGT persists intracellularly for weeks, providing sustained protection against UV-induced oxidative damage. By inhibiting MMP-1 and MMP-3 expression in UV-exposed fibroblasts, it serves as a powerful matrix shield that preserves collagen integrity and prevents photoaging.

Available Purity Grades

• L-Ergothioneine 50% 70% (HPLC) — Liposomal powder with phosphatidylcholine encapsulation for enhanced bioavailability.

Why Choose Our Liposomal L-Ergothioneine?

• Dedicated Transporter Accumulation: Exploits the OCTN1 (SLC22A4) transporter for selective, active uptake into skin cells—meaning EGT is concentrated exactly where protection is needed most, unlike passively absorbed antioxidants.
• Persistent Intracellular Antioxidant: With a cellular half-life of approximately 30 days, ergothioneine provides continuous free radical scavenging long after topical application, outlasting vitamin C, glutathione, and polyphenols.
• MMP Inhibition: Suppresses UV-induced expression of collagen-degrading MMP-1, MMP-3, and MMP-9 in dermal fibroblasts, preventing the breakdown of existing collagen and elastin fibers in photoaged skin.
• Thiols Protection: Specifically protects critical cysteine residues in structural proteins and enzymes from oxidation, maintaining the functional integrity of the dermal extracellular matrix.
• Anti-Inflammatory Cascade: Dampens NF-κB signaling and reduces pro-inflammatory cytokines IL-6 and IL-8 in UV-stressed keratinocytes, breaking the inflammation-aging cycle at its source.
• Blue Light & Infrared Defense: EGT neutralizes reactive oxygen species generated by visible blue light and infrared radiation from screens and devices, addressing modern photoaging threats beyond traditional UV protection.

Target Applications

• Photoaging Defense Brands: Companies developing day creams and serums targeting UV, blue light, and infrared-induced collagen degradation with a long-lasting, transporter-targeted antioxidant.
• Premium Daily Skincare Lines: Brands seeking a science-forward active ingredient that provides 30-day residual antioxidant protection, differentiating from conventional vitamin C or polyphenol-based formulations.

Quality & Compliance

• GMP-certified production facilities
• Liposomal encapsulation verified by DLS particle size analysis
• COA provided with every shipment
• Heavy metals compliant (Pb ≤ 2 ppm, As ≤ 1 ppm)
• Custom packaging and private labeling available
• Stable shelf life: 24 months (cool, dry storage, protected from light)

Bulk Supply & OEM Service

We supply liposomal L-Ergothioneine in bulk quantities (sample to 25 kg drums) for B2B buyers, contract manufacturers, and private-label brands. Contact our technical team for quotes, sample requests, or formulation consultation.